In order to promote Engineering education to the people of interior Sindh at their door step, the Government of Sindh established a constituent college of Mehran University of Engineering & Technology named as “Mehran University College of Engineering & Technology, Khairpur Mir’s”. The college has been upgraded as a Campus of Mehran University of Engineering & Technology, Jamshoro, and renamed as “Mehran University of Engineering & Technology, Shaheed Zulfiqar Ali Bhutto Khairpur Mir’s Campus”
The postgraduate courses were started in the University in 1978 leading to Master’s Degree, initially, in three branches. At present, courses are offered in the specialized fields of ‘Structural Engineering, Civil Engineering, Geo-technical and Highway Engineering, Construction Management, City and Regional Planning, Irrigation and Drainage Engineering, Environmental Engineering & Management, Manufacturing Engineering, Energy Systems Engineering , Chemical Engineering, Industrial Engineering & Management, Mining Engineering, Metallurgy and Materials Engineering, Telecommunication and Control Engineering, Telecommunication Engineering & Management, Communication Systems Network, Information Technology, Telemedicine & e-Health Systems, Software Engineering, Computer & Information Technology, Electrical Power Engineering and Electronic System Engineering. Some courses are offered full time during the day while others are conducted during the evenings. The degrees to be awarded may be Post-graduate Diploma (P.G.D.), Master of Engineering (M.E.), Master of Science (M.S), Master of Philosophy (M. Phil.) or Doctor of Philosophy (Ph.D.); depending upon the quality and quantity of the research/work completed.